It generates confusion among biochemists and doctors to embrace change of the reference values \u200b\u200b(VF) for hormones hLH and hFSH, at the end of the decade of the 80 techniques immunometric (IRMA) provide numerous advantages in sensitivity, specificity, reproducibility and increased detection range over competitive techniques (RIA). When everything seemed to be solved, there are changes, new problems and end an important solution for clinical diagnosis. The paradigm changed again.
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